Peripheral nervous system damage in coronavirus infection: a review of the literature
https://doi.org/10.56618/2071-2693_2024_16_1_133
EDN: EVLDXL
Abstract
The article is devoted to the issues of peripheral nervous system lesions after a new coronavirus infection. Among the nosologic forms there are mononeuropathies, multineuropathies, as well as polyneuropathies, which are noted both in the acute period and in the development of the post-acute syndrome. A literature review is presented to establish a possible causal relationship between novel coronavirus infection and peripheral nervous system lesions.
About the Authors
N. V. Amosova
North-Western district scientific and clinical center named after L. G. Sokolov
Russian Federation
Russian Federation
Amosova Nadezhda Vladimirovna,
4, Kultury Pr., St. Petersburg, 194291.
S. S. Kucherenko
North-Western district scientific and clinical center named after L. G. Sokolov; V. A. Almazov National Medical Research Center
Russian Federation
Russian Federation
Kucherenko Stanislav Sergeevich,
4, Kultury Pr., St. Petersburg, 194291.
2, Akkuratova street, St. Petersburg, 197341.
N. E. Ivanova
V. A. Almazov National Medical Research Center
Russian Federation
Russian Federation
Ivanova Nataliya Evgen’evna,
2, Akkuratova street, St. Petersburg, 197341.
T. M. Alekseeva
V. A. Almazov National Medical Research Center
Russian Federation
Russian Federation
Alekseeva Tatyana Mikhailovna,
2, Akkuratova street, St. Petersburg, 197341.
References
1. World Healh Organization. Available from: https://www.who.int/news-room/detail/30-01-2020-statement-on-thesecond-meeting-of-theinternational-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-ofnovelcoronavirus-(2019-nCoV) [Accessed 6 October 2023].
2. Cucinotta D., Vanelli M.. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020;91(1):157–160. Doi: https://doi.org/10.23750/abm.v91i1.9397. PMID: 32191675; PMCID: PMC7569573.
3. World Healh Organization. Coronavirus disease (COVID-19) Weekly Epidemiological Updates and Monthly Operational Updates. Accessed March, 2020. Available from: https://www.who.int/emergencies/diseases/novelcoronavirus 2019/situation-reports [Accessed 6 October 2023].
4. Временные методические рекомендации. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). 2022. С. 7–8. [Vremennye metodicheskie rekomendacii. Profilaktika, diagnostika i lechenie novoj koronavirusnoj infekcii (COVID-19). 2022. Р. 7–8. (In Russ)].
5. Карта коронавируса Covid-19 онлайн. URL: https://yandex.ru/maps/covid19?ll=49.773925%2C52.017013&z=2.8 (дата обращения: 14.09.2023). [Covid-19 coronavirus map online. Available from: https://yandex.ru/maps/covid19?ll=49.773925%2C52.017013&z=2.8 (Accessed 14 September 2023)].
6. Хайтович А. Б. Коронавирусы (структура генома, репликация) // Крым. журн. клин. и эксперимент. мед. 2020. Т. 10, № 4. С. 78–95. [Hajtovich A. B. Koronavirusy (struktura genoma, replikaciya). Krymskij zhurnal klinicheskoj i eksperimental’noj mediciny. 2020;10(4):78–95. (In Russ.)].
7. Lan J., Ge J., Yu J., Shan S., Zhou H., Fan S., Zhang Q., Shi X., Wang Q., Zhang L., Wang X. Structure of the SARSCoV-2 spike receptor-binding domain bound to the ACE2 receptor. Nature. 2020;581(7807):215–220. https://doi.org/10.1038/s41586-020-2180-5. PMID: 32225176.
8. Graham R. L., Baric R. S. Minireview Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species Transmission. Journal of Virology. 2010; 84(7):3134–3146. https://doi.org/10.1128/JVI.01394-09.
9. Wang K., Chen W., Zhang Z., Deng Y., Lian J. Q., Du P., Wei D., Zhang Y., Sun X. X., Gong L., Yang X., He L., Zhang L., Yang Z., Geng J. J., Chen R., Zhang H., Wang B., Zhu Y. M., Nan G., Jiang J. L., Li L., Wu J., Lin P., Huang W., Xie L., Zheng Z. H., Zhang K., Miao J. L., Cui H. Y., Huang M., Zhang J., Fu L., Yang X. M., Zhao Z., Sun S., Gu H., Wang Z., Wang C. F., Lu Y., Liu Y. Y., Wang Q. Y., Bian H., Zhu P., Chen Z. N. CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells. Signal Transduct Target Ther. 2020;5(1):283. https://doi.org/10.1038/s41392-020-00426-x. PMID: 33277466; PMCID: PMC7714896.
10. Mao L., Jin H., Wang M., Hu Y., Chen S., He Q., Chang J., Hong C., Zhou Y., Wang D., Miao X., Li Y., Hu B. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683–690. https://doi.org/10.1001/jamaneurol.2020.1127. PMID: 32275288; PMCID: PMC7149362.
11. Chu H., Chan J. F., Yuen T. T., Shuai H., Yuan S., Wang Y., Hu B., Yip C. C., Tsang J. O., Huang X., Chai Y., Yang D., Hou Y., Chik K. K., Zhang X., Fung A. Y., Tsoi H. W., Cai J. P., Chan W. M., Ip J. D., Chu A. W., Zhou J., Lung D. C., Kok K. H., To K. K., Tsang O. T., Chan K. H., Yuen K. Y. Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study. Lancet Microbe. 2020;1(1):14–23. https://doi.org/10.1016/S2666-5247(20)30004-5. Epub 2020 Apr 21. PMID: 32835326; PMCID: PMC7173822.
12. Matschke J., Lütgehetmann M., Hagel C., Sperhake J. P., Schröder A. S., Edler C., Mushumba H., Fitzek A., Allweiss L., Dandri M., Dottermusch M., Heinemann A., Pfefferle S., Schwabenland M., Sumner Magruder D., Bonn S., Prinz M., Gerloff C., Püschel K., Krasemann S., Aepfelbacher M., Glatzel M. Neuropathology of patients with COVID-19 in Germany: a post-mortem case series. Lancet Neurol. 2020;19(11):919–929. https://doi.org/10.1016/S1474-4422(20)30308-2. Epub 2020 Oct 5. PMID: 33031735; PMCID: PMC7535629.
13. Paniz-Mondolfi A., Bryce C., Grimes Z., Gordon R. E., Reidy J., Lednicky J., Sordillo E. M., Fowkes M. Central nervous system involvement by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). J Med Virol. 2020;92(7):699–702. https://doi.org/10.1002/jmv.25915. PMID: 32314810; PMCID: PMC7264598.
14. Iba T., Connors J. M, Levy J. H. The coagulopathy, endotheliopathy, and vasculitis of COVID-19. Inflamm Res. 2020;69(12):1181–1189. https://doi.org/10.1007/s00011-020-01401-6. Epub 2020 Sep 12. PMID: 32918567; PMCID: PMC7486586.
15. Domingues R. B., Mendes-Correa M. .C., de Moura Leite F. B. V., Sabino E. C., Salarini D. Z., Claro I., Santos D. W., de Jesus J. G., Ferreira N. E., Romano C. M., Soares C. A. S. First case of SARS-COV-2 sequencing in cerebrospinal fluid of a patient with suspected demyelinating disease. J Neurol. 2020;267(11):3154–3156. https://doi.org/10.1007/s00415-020-09996-w. PMID: 32564153; PMCID: PMC7305694.
16. Ellul M. A., Benjamin L., Singh B., Lant S., Michael B. D., Easton A., Kneen R., Defres S., Sejvar J., Solomon T. Neurological associations of COVID-19. Lancet Neurol. 2020;19(9):767–783. https://doi.org/10.1016/S1474-4422(20)30221-0. PMID: 32622375; PMCID: PMC7332267.
17. Uversky V. N., Elrashdy F., Aljadawi A., Ali S. .M, Khan R. H., Redwan E. M. Severe acute respiratory syndrome coronavirus 2 infection reaches the human nervous system: How? J Neurosci Res. 2021;99(3):750–777. https://doi.org/10.1002/jnr.24752. PMID: 33217763; PMCID: PMC7753416.
18. COVID-19 rapid guideline: managing the long-term effects of COVID-19. London: National Institute for Health and Care Excellence (NICE); 2020. Dec 18. PMID: 33555768.
19. Melamed E., Rydberg L., Ambrose A. F., BhavarajuSanka R., Fine J. S., Fleming T. K., Herman E., Phipps Johnson J. L., Kucera J. R., Longo M., Niehaus W., Oleson C. .V., Sampsel S., Silver J. K., Smith M. M., VerduzcoGutierrez M. Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of neurologic sequelae in patients with post-acute sequelae of SARS-CoV-2 infection (PASC). PMR. 2023;15(5):640–662. PMID: 36989078.
20. Eissa M., Abdelhady M., Alqatami H., Salem K.., Own A, El Beltagi A. H. Spinal cord infarction in a 41-year-old male patient with COVID-19. Neuroradiol J. 2021;34(3):245–248. https://doi.org/10.1177/1971400921988925. PMID: 33480310; PMCID: PMC8165895.
21. Qazi R., Memon A., Mohamed A. S., Ali M., Singh R. PostCOVID-19 Acute Transverse Myelitis: A Case Report and Literature Review. Cureus. 2021;13(12):e20628. https://doi.org/10.7759/cureus.20628. PMID: 35106196; PMCID: PMC8786584.
22. Kim Y., Heo D., Choi M., Lee J. M. A Case Presenting with Neuromyelitis Optica Spectrum Disorder and Infectious Polyradiculitis Following BNT162b2 Vaccination and COVID-19. Vaccines (Basel). 2022;10(7):1028. https://doi.org/10.3390/vaccines10071028. PMID: 35891192; PMCID: PMC9321122.
23. Paliwal V. K., Garg R. K., Gupta A., Tejan N. Neuromuscular presentations in patients with COVID-19. Neurol Sci. 2020;41(11):3039–3056. https://doi.org/10.1007/s10072-020-04708-8. Epub 2020 Sep 15. PMID: 32935156; PMCID: PMC7491599.
24. Vaira L. A., Salzano G., Deiana G., De Riu G. Anosmia and Ageusia: Common Findings in COVID-19 Patients. Laryngoscope. 2020;130(7):1787. https://doi.org/10.1002/lary.28692. PMID: 32237238; PMCID: PMC7228304.
25. Nalleballe K., Reddy Onteddu S., Sharma R., Dandu V.., Brown A, Jasti M., Yadala S., Veerapaneni K., Siddamreddy S., Avula A., Kapoor N., Mudassar K., Kovvuru S. Spectrum of neuropsychiatric manifestations in COVID-19. Brain Behav Immun. 2020;88:71–74. https://doi.org/10.1016/j.bbi.2020.06.020. PMID: 32561222; PMCID: PMC7297688.
26. Liotta E. M., Batra A., Clark J. R., Shlobin N. A., Hoffman S. C., Orban Z. S., Koralnik I. J. Frequent neurologic manifestations and encephalopathy-associated morbidity in Covid-19 patients. Ann Clin Transl Neurol. 2020;7(11):2221–2230. https://doi.org/10.1002/acn3.51210. PMID: 33016619; PMCID: PMC7664279.
27. Frontera J. A., Sabadia S., Lalchan R., Fang T., Flusty B., Millar-Vernetti P., Snyder T., Berger S., Yang D., Granger A., Morgan N., Patel P., Gutman J., Melmed K., Agarwal S., Bokhari M., Andino A., Valdes E., Omari M., Kvernland A., Lillemoe K., Chou S. H., McNett M., Helbok R., Mainali S., Fink E. L., Robertson C., Schober M., Suarez J. I., Ziai W., Menon D., Friedman D., Friedman D., Holmes M., Huang J., Thawani S., Howard J., Abou-Fayssal N., Krieger P., Lewis A., Lord A. S., Zhou T., Kahn D. E., Czeisler B. M., Torres J., Yaghi S., Ishida K., Scher E., de Havenon A., Placantonakis D., Liu M., Wisniewski T., Troxel AB., Balcer L., Galetta S. A Prospective Study of Neurologic Disorders in Hospitalized Patients With COVID-19 in New York City. Neurology. 2021;96(4):e575–e586. https://doi.org/10.1212/WNL.0000000000010979. PMID: 33020166; PMCID: PMC7905791.
28. Guerrero J. I., Barragán L. A., Martínez J. D., Montoya J. P., Peña A., Sobrino F. E., Tovar-Spinoza Z., Ghotme K. A. Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings. BMC Infect Dis. 2021;21(1):515. https://doi.org/10.1186/s12879-021-06185-6. PMID: 34078305; PMCID: PMC8170436.
29. Doblan A., Kaplama M. E., Ak S., Basmacı N., Tarini E. Z., Göktaş Ş. E., Güler S., Müderris T. Cranial nerve involvement in COVID-19. Am J Otolaryngol. 2021;42(5):102999. https://doi.org/10.1016/j.amjoto.2021.102999. PMID: 33838359; PMCID: PMC7997027.
30. Малько В. А., Климов П. В., Топузова М. П. и др. Синдром Миллера Фишера, развившийся после перенесенной инфекции COVID-19 (клинический случай) // Нервно-мышечные болезни. 2021. Т. 11, № 2. С. 56–60. [Mal’ko V. A., Klimov P. V., Topuzova M. P.et al. Sindrom Millera Fishera, razvivshijsya posle perenesennoj infekcii COVID-19 (klinicheskij sluchaj). Nervno-myshechnye bolezni 2021;11(2):56–60. (In Russ.)]. https://doi.org/10.17650/2222-8721-2021-11-2-56-60.
31. Власенко А. И., Портик О. А., Бисага Г. Н. и др. Взаимосвязь между вирусом SARS-COV-2 и аутоиммунными неврологическими заболеваниями // Журнал инфектологии. 2022. Т. 14, № 2. С. 65–72. [Vlasenko A. I., Portik O. A., Bisaga G. N. et al. Vzaimosvyaz’ mezhdu virusom SARS-COV-2 i autoimmunnymi nevrologicheskimi zabolevaniyami. Zhurnal Infektologii. 2022;14(2):65–72. (In Russ.)]. https://doi.org/10.22625/2072-6732-2022-14-2-65-72.
32. Finsterer J., Scorza F. A., Scorza C., Fiorini A. COVID-19 associated cranial nerve neuropathy: A systematic review. Bosn J Basic Med Sci. 2022;22(1):39–45. https://doi.org/10.17305/bjbms.2021.6341. PMID: 34392827; PMCID: PMC8860318.
33. Hegna E., Rački V., Hero M., Papić E., Rožmarić G., Radović K., Komen V., Bralić M., Škifić M. L., Bonifačić D., Tomić Z., Perković O., Vuletić V. Post-COVID-19 Syndrome in Neurology Patients: A Single Center Experience. Pathogens. 2023;12(6):796. https://doi.org/10.3390/pathogens12060796. PMID: 37375486; PMCID: PMC10302491.
34. Pilotto A., Cristillo V., Cotti Piccinelli S., Zoppi N., Bonzi G., Sattin D., Schiavolin S., Raggi A., Canale A., Gipponi S., Libri I., Frigerio M., Bezzi M., Leonardi M., Padovani A. Long-term neurological manifestations of COVID-19: prevalence and predictive factors. Neurol Sci. 2021;42(12):4903–4907. https://doi.org/10.1007/s10072-021-05586-4. PMID: 34523082; PMCID: PMC8439956.
35. Frithiof R., Rostami E., Kumlien E., Virhammar J., Fällmar D., Hultström M., Lipcsey M., Ashton N., Blennow K., Zetterberg H., Punga A. R. Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: A prospective study. Clin Neurophysiol. 2021;132(7):1733–1740. https://doi.org/10.1016/j.clinph.2021.03.016. PMID: 33875374; PMCID: PMC8012169.
36. Anderson-Smits C., Ritchey M. E., Huang Z., Chavan S., Souayah N., Ay H., Layton J. B. Intravenous Immunoglobulin Treatment Patterns and Outcomes in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A US Claims Database Analysis. Neurol Ther. 2023;12(4):1119–1132. https://doi.org/10.1007/s40120-023-00478-5. PMID: 37171778; PMCID: PMC10310601.
37. Hänggi P., Aliu B., Martin K., Herrendorff R., Steck A. J. Decrease in Serum Anti-MAG Autoantibodies Is Associated With Therapy Response in Patients With Anti-MAG Neuropathy: Retrospective Study. Neurol Neuroimmunol Neuroinflamm. 2021;9(1):e1109. https://doi.org/10.1212/NXI.0000000000001109. PMID: 34759022; PMCID: PMC8587733.
38. Aroori S., Spence R. A. Carpal tunnel syndrome. Ulster Med J. 2008;77(1):6–17. PMID: 18269111; PMCID: PMC2397020.
39. Белова Н. В., Юсупова Д. Г., Лагода Д. Ю. и др. Современные представления о диагностике и лечении карпального туннельного синдрома // РМЖ. 2015. № 24. С. 1429–1432. [Belova N. V., YUsupova D. G., Lagoda D. Yu., Vershinin A. V., Vujcik N. B., Suponeva N. A., Arestov S. O., Gushcha A. O. Sovremennye predstavleniya o diagnostike i lechenii karpal’nogo tunnel’nogo sindroma RMZH. 2015;(24):1429–1432. (In Russ.)].
40. Michelsen H., Posner M. A. Medical history of carpal tunnel syndrome. Hand Clin. 2002;18(2):257–268. https://doi.org/10.1016/s0749-0712(01)00006-3. PMID: 12371028.
41. Ibrahim I., Khan W. S., Goddard N., Smitham P. Carpal tunnel syndrome: a review of the recent literature. Open Orthop J. 2012;(6):69–76. https://doi.org/10.2174/1874325001206010069. PMID: 22470412; PMCID: PMC3314870.
42. Deniz F. E., Oksüz E., Sarikaya B., Kurt S., Erkorkmaz U., Ulusoy H., Arslan S. Comparison of the diagnostic utility of electromyography, ultrasonography, computed tomography, and magnetic resonance imaging in idiopathic carpal tunnel syndrome determined by clinical findings. Neurosurgery. 2012;70(3):610–6. https://doi.org/10.1227/NEU.0b013e318233868f. PMID: 21869718.
43. Никищенкова А. С., Жулёв С. Н., Зайчик А. М. и др. Патогенетические особенности развития туннельных невропатий у больных с гипотиреозом // Вестн. Северо-Запад. гос. мед. ун-та им. И. И. Мечникова. 2012. Т. 4, № 3. С. 73–76. [Ikishchenkova A. S., ZHulyov S. N., Zajchik A. M., Halimov Yu. Sh., Zagrebel’naya O. A., Guzalov P. I., Karpenko A. K., Zhulyov N. M. Patogeneticheskie osobennosti razvitiya tunnel’nyh nevropatij u bol’nyh s gipotireozom. Vestnik SeveroZapadnogo gosudarstvennogo medicinskogo universiteta im. I. I. Mechnikova. 2012;4(3):73–76. (In Russ.)].
44. Никитин С. С., Маслак А. А., Куренков А. Л. Особенности диагностики синдрома карпального канала с помощью электромиографии и ультразвукового исследования // Анналы клин. и эксперимент. неврологии. 2013. Т. 7, № 4. С. 20–26. [Nikitin S. S., Maslak A. A., Kurenkov A.L. et al. Osobennosti diagnostiki sindroma karpal’nogo kanala s pomoshch’yu elektromiografii i ul’trazvukovogo issledovaniya. Annaly klinicheskoj i eksperimental’noj nevrologii. 2013;7(4):20–26. (In Russ.)].
45. Atroshi I., Flondell M., Hofer M., Ranstam J. Methylprednisolone injections for the carpal tunnel syndrome: a randomized, placebo-controlled trial. Ann Intern Med. 2013;159(5):309–317. https://doi.org/10.7326/0003-4819-159-5-201309030-00004. PMID: 24026316.
46. Ono S., Clapham P. J., Chung K. C. Optimal management of carpal tunnel syndrome. Int J Gen Med. 2010;(3):255–261. https://doi.org/10.2147/ijgm.s7682. PMID: 20830201; PMCID: PMC2934608.
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Amosova N.V., Kucherenko S.S., Ivanova N.E., Alekseeva T.M. Peripheral nervous system damage in coronavirus infection: a review of the literature. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2024;16(1):133-140. (In Russ.) https://doi.org/10.56618/2071-2693_2024_16_1_133. EDN: EVLDXL
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