Features of the course and diagnosis of a brain tumor during pregnancy
Abstract
The actual problem of neurology and neurosurgery is the study of pathogenesis, improvement of diagnosis, treatment of brain tumors. Great importance is attached to issues of differential diagnosis of neurological pathology during pregnancy, early detection of brain tumors, which can be the cause of maternal mortality, prematurity, fetal loss syndrome. Clinical practice shows that complaints of a pregnant woman for headache, fatigue, nausea and vomiting during the first trimester of pregnancy are often considered by obstetrician-gynecologists and, often, by neurologists as manifestations of toxicosis; with the development of visual impairment, altered consciousness, convulsive seizures in the second half of pregnancy and in the postpartum period as preeclampsia, eclampsia, which greatly complicates timely diagnosis and rational treatment. In this regard, the purpose of the publication was to review the survey data from 5 cases of diagnosis of a brain tumor during pregnancy in patients admitted to a multidisciplinary hospital, and a review of the literature.
About the Authors
M. L. ChukhlovinaRussian Federation
St Petersburg
N. N. Volkov
Russian Federation
St Petersburg
S. E. Medvedev
Russian Federation
St Petersburg
V. N. Volkova
Russian Federation
St Petersburg
References
1. Воинов Н.Е., Улитин А. Ю., Лавровский П. В., Нечаева А. С. Потёмкина В. Г., Олюшин В. Е., Бахтиер Б. Первично-множественные церебральные опухоли различной гистологической структуры (описание клинических случаев). Российский нейрохирургический журнал имени профессора А. Л. Поленова. — 2020. — Т. 12. — № 1. С. 55–63.
2. Зрелов А.А., Куканов К. К., Самочёрных К. А., Улитин А. Ю., Нечаева А. С., Тастанбеков М. М. Использование эндоскопических и стереотаксического методов в хирургии опухолей головного мозга (клинические случаи). Российский нейрохирургический журнал имени профессора А. Л. Поленова. — 2020. — Т. 12. — № 2. С. 48–52.
3. Парфёнов В. А. Неврологические расстройства при соматических заболеваниях и беременности. Болезни нервной системы. Руководство для врачей. Под ред. Н. Н. Яхно, Д. Р. Штульмана. М. Медицина, 2001, Т. 2. с. 317–350.
4. Краско А.С., Михайлова Н. Ф., Одинцова Г. В., Михайлов В. А., Иванова Н. Е. Эпилепсия и беременность: нейроповеденческая тератогенность (обзор литературы). Российский нейрохирургический журнал имени профессора А. Л. Поленова. — 2020. — Т. 12. — № 3. С. 55–60.
5. Дяченко А.А., Субботина А. В., Измалов Т. Р., Красильников А. В., Вальков М. Ю. Эпидемиология первичных опухолей головного мозга: (обзор литературы). Вестник РНЦРР МЗ РФ. № 13. 2013:1–37.
6. Srytrova P, Bydzovska I. Anaplastic astrocytoma in pregnancy. Ceska Gynekol. Summer 2018;83(2):119–122.
7. Gustafsson HC, Sullivan EL, Nousen EK, Sullivan CA, Huang E, Rincon M, Nigg JT, Loftis JM. Maternal prenatal depression predicts infant negative affect via maternal inflammatory cytokine levels. Brain Behav Immun. 2018 Oct; 73 (10):470–481. doi: 10.1016/j.bbi.2018.06.011.
8. Zwinkels H, Dörr J, Kloet F, Taphoorn MJ, Vecht CJ. Pregnancy in women with gliomas: a case-series and review of the literature. J Neurooncol. 2013;115 (2):293–301. doi:10.1007/s11060-013-1229-9.
9. Bicocca MJ, Gilbert AR, Sadrameli SS, Pirics ML. Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy. Case Reports in Obstetrics and Gynecology. 2018:(5) 4606354. doi:10.1155/2018/4606354.
10. van Westthenen A, Senders JT, Martin E, DiRisio AC, Broekman MLD. et al. Clinical challenges of glioma and pregnancy: a systematic review. Journal of Neuro-Oncology. 2018;139 (1):1–11. http://doi.org/10.1007/s11060-018-2851-3.
11. Yust-Katz S, de Groot JF, Liu D, Wu J, Yuan Y, Anderson MD, Conrad CA, Milbourne A, Gilbert MR, Armstrong TS. Pregnancy and glial brain tumors. Neuro-Oncology. 2014;16(9):1289–1294. doi:10.1093/neuonc/nou019.
12. Tavares CB, Gomes-Braga FC, Costa-Silva DR, Escorcio-Dourado CS, Borges US, Conde-Junior AM. Expression of estrogen and progesterone receptors in astrocytomas: a literature review. Clinics. 2016;71 (8):481–486. doi:10.6061/clinics/2016(08)12.
13. Gutierrez-Rodriguez A, Hansberg-Pastor V, Camacho-Arroyo I. Proliferative and invasive effect of progesterone-induced blocking factor in human glioblastoma cell. BioMed Research International. 2017. http://dx.doi.org/10.1155/2017/1295087.
14. Gurcay AG, Bozkurt I, Senturk S, et al. Diagnosis, Treatment and Management Strategy of Meningioma during Pregnancy. Asian J Neurosurg. 2018; 13 (1):86–89. doi: 10.4103/1793–5482.181115.
15. Trinca F, Inácio M, Timóteo T, Dinis R. Triple-negative breast cancer with brain metastasis in a pregnant woman.BMJ Case Rep. 2017 Feb 20; 2017 (2). pii: bcr2016218657. doi: 10.1136/bcr-2016–218657.
16. Singh P., Mantilla E., Sewell J, Hatanpaa KJ, Pan E. Occurrence of Glioma in Pregnant Patients: An Institutional Case Series and Review of the Literature. Anticancer Res. 2020 Jun; 40(6):3453–3457. doi: 10.21873/anticanres.14331.
17. Eckenstein M, Thomas AA. Benign and malignant tumors of the central nervous system and pregnancy. Handb Clin Neurol. 2020; 172 (2):241–258. doi: 10.1016/B978-0-444-64240-0.00014–3.
18. Romanelli P, Paiano M, Crocamo V. Staged Image-guided Robotic Radiosurgery and Deferred Chemotherapy to Treat a Malignant Glioma During and After Pregnancy. Muacevic A, Adler JR, eds. Cureus. 2018; 10(2): e2141. doi:10.7759/cureus.2141.
19. Burotto M, Gormaz JG, Samtani S, Valls N, Silva R, Rojas C, Portino S, de la Jara C. Viable Pregnancy in a patient with metastatic melanoma treated with double checkpoint immunotherapy.Semin Oncol. 2018 Jun; 45(3):164–169. doi: 10.1053/j.seminoncol.2018.03.003.
20. Кондратьева Е.А., Кондратьев С. А., Смирнов П. В. Бугорский Е. В., Алексеева Т. М., Тастанбеков М., Иванова Н. Е., Данилов Ю. П., Улитин А. Ю., Шляхто Е. В. Стимуляции в коррекции атаксии у пациентов после резекции больших и гигантских вестибулярных шванном. Российский нейрохирургический журнал имени профессора А. Л. Поленова. — 2018. — Т. 10. — № 2. С. — 42–47.
21. Peyser A, Bristow SL, Hershlag A. Two successful pregnancies following fertility preservation in a patient with anaplastic astrocytoma: a case report. BMC Cancer. 2018;18 (1):544.http://doi.org/10/1186/s12885–018–44.
Review
For citations:
Chukhlovina M.L., Volkov N.N., Medvedev S.E., Volkova V.N. Features of the course and diagnosis of a brain tumor during pregnancy. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2021;13(1):75-79. (In Russ.)