Modeling the volume of tissue activated using directional deep brain stimulation
https://doi.org/10.56618/2071-2693_2023_15_1_52
Abstract
SUMMARY. The use of segmented electrodes in deep brain stimulation (DBS) systems in stereotaxis has proven to be effective against undesirable side effects by changing the stimulation vector. Appearance of modern algorithms for calculating the volume of tissue activated (VTA) around the active contact of the electrode allowed better understanding how stimulation affects the activity of target brain structures. We evaluated the results of VTA modeling using segmented electrodes for deep stimulation implanted in the Globus Pallidum and the Subthalamic nucleus. Activation of the DBS system in the directional stimulation mode at the same amplitude values allowed using more structures in the direction of stimulation than in the non-directional mode, while reducing the involvement of structures around inactive contacts. With a suboptimal position of the electrode, it is possible to achieve the involvement of the required stereotactic target by the activation volume only with a significant increase in amplitude; operation in the directed stimulation mode can improve the results, but the accuracy of electrode implantation still plays a key role in the effectiveness of the operation.
Supporting agencies: The study was performed without external funding.
About the Authors
V. A. Peskov
N.P. Bekhtereva Institute of Human Brain of the Russian Academy of Sciences
Russian Federation
Russian Federation
Peskov Viktor Alexandrovich
9, Akademika Pavlova st., Saint Petersburg, 197376
A. I. Kholyavin
N.P. Bekhtereva Institute of Human Brain of the Russian Academy of Sciences
Russian Federation
Russian Federation
Kholyavin Andrey Ivanovich
9, Akademika Pavlova st., Saint Petersburg, 197376
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Review
For citations:
Peskov V.A., Kholyavin A.I. Modeling the volume of tissue activated using directional deep brain stimulation. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2023;15(1):52-55. (In Russ.) https://doi.org/10.56618/2071-2693_2023_15_1_52
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