Recurrent intracranial meningiomas (review and clinical case report)

INTRODUCTION. Meningiomas are the second most common central nervous system (СNS) tumors after gliomas in adults. The overall rate of meningioma recurrence is 14–33 % according to different authors.

PURPOSE. To discuss the challenges in diagnosis and treatment of recurrent meningiomas, to assess the clinical features and adjuvant treatment options. To present a clinical case of comprehensive treatment of intracranial meningioma recurrence.

MATERIAL AND METHODS. We searched for publications in the Pubmed, EMBASE, Cohrane Library and eLibrary databases published between January 2000 and January 2019 on the issue of recurrent intracranial meningiomas, in particular atypical and anaplastic meningiomas. The clinical case of supratentorial meningioma recurrence is reported.

RESULTS. The review systematizes data on the prognostic factors for survival, relapse-free period, and disease progression. Particular attention was paid to the radical resection of the tumor and the assessment of the grade of anaplasia. The current data on adjuvant treatment options were presented. The controversial issues of approaches to the assessment of morphological prognostic criteria were discussed.

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