Factors influencing of epilepsy after eloquent brain tumor resection in children
https://doi.org/10.56618/2071-2693_2023_15_2_109
Abstract
Summary. 20 % of supratentorial tumors are located in eloquent brain area. The aim of the neurosurgical treatment is to do gross total resection of the neoplasm. Gross total removal is the main factor of a favorable prognosis, improving not only survival, but also the possibility of ridding the patient of epilepsy associated with the tumor. Purpose of the study: to study the outcome of epilepsy and the factors affecting it in patients witch operated eloquent brain area tumors (EBATs). Materials and methods: The study included 68 patients with tumors of eloquent brain area. Epilepsy was diagnosed in 54 (79.4 %). Median age is 11.8 years. The follow–up period before surgical treatment was 2.93 years. Results. After surgery, no seizures were registered or the result of Engel I in 60 (88.2 %) patients, (p<0.001). In a single-variant analysis, it was found that the factors influencing of epilepsy after surgery are: gross total removal of the tumor, p=0.0362 and p=0.0478 for low-grade gliomas (LGG), as well as epilepsy of duration less than three years, p=0.0011. Multivariate regression confirmed the statistical significance of the gross total removal of the tumor p=0.0086 and the duration of epilepsy before surgery, p=0.0008. Epilepsy associated with the operation was in one (7.1 %) cases. Conclusion. The study identify two main factors influencing the outcome of epilepsy in patients with eloquent brain area tumors in children, these are the duration of the epilepsy and gross total removal of the tumor.
About the Authors
M. V. Talabaev
Republican Research and Clinical Center for Neurology and Neurosurgery
Belarus
Belarus
24 F. Skoriny, Minsk, Republic of Belarus, 220114
S. L. Kulikova
Republican Research and Clinical Center for Neurology and Neurosurgery
Belarus
Belarus
24 F. Skoriny, Minsk, Republic of Belarus, 220114
G. V. Zabrodzets
Republican Research and Clinical Center for Neurology and Neurosurgery
Belarus
Belarus
24 F. Skoriny, Minsk, Republic of Belarus, 220114
H. Y. Salauyeva
Republican Research and Clinical Center for Neurology and Neurosurgery
Belarus
Belarus
24 F. Skoriny, Minsk, Republic of Belarus, 220114
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Review
For citations:
Talabaev M.V., Kulikova S.L., Zabrodzets G.V., Salauyeva H.Y. Factors influencing of epilepsy after eloquent brain tumor resection in children. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2023;15(2):109-115. (In Russ.) https://doi.org/10.56618/2071-2693_2023_15_2_109
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