Occipital-lobe epilepsy associated with intraparenchymal schwannoma in the occipital lobe: a modern perspective on the problem
https://doi.org/10.56618/2071-2693_2024_16_2_138
EDN: KHHQWN
Abstract
This article is dedicated to the problem of occipital lobe epilepsy associated with intraparenchymal occipital schwannoma localization. The peculiarity is that occipital lobe epilepsy accounts for less than 10% of all forms of locally determined (partial) epilepsies, which is why some authors doubt its existence. Nevertheless, occipital lobe epilepsy is the second most frequent manifestation of such a rare condition as intraparenchymal occipital schwannoma localized in the occipital lobe. In our study, 15 clinical cases describing intraparenchymal occipital and occipital/temporal localization of schwannoma were analyzed, and up-to-date information on the pathogenesis, clinical presentation, diagnosis, and treatment of occipital lobe epilepsy and intraparenchymal occipital schwannoma was presented. The conclusions were made about confirming the existence of occipital lobe epilepsy and the need for further research in order to expand knowledge about this pathology and develop modern treatment methods.
Aim – to analyze clinical cases of occipital lobe epilepsy associated with intraparenchymal occipital lobe schwannoma.
According to the results of our analysis of known clinical cases, we found that epileptic seizures are the second most frequent symptom in the clinical presentation of intraparenchymal occipital and occipitoparietal schwannoma. Thus, this cannot but prove the possibility of diagnosing “occipital epilepsy.”
Occipitoparietal epilepsy is the rarest form of locally determined (focal) epilepsy, and according to some authors, it does not exist at all. The existence of occipital epilepsy as a diagnosis is confirmed by the fact that it is the second most frequent symptom detected in patients with intraparenchymal occipital lobe schwannoma. Undoubtedly, further clinical observations, morphological and genetic studies will expand the etiopathogenetic understanding of existing locally determined occipital forms of epilepsy associated with tumor processes, which in turn will allow us to approach the development of modern strategies for personalized treatment of occipital epilepsy.
About the Authors
A. V. VasilenkoRussian Federation
Anna V. Vasilenko – Head of Educational Department, Associate Professor, Chair of Neurosurgery, Institute of Medical Education; Associate Professor, Davidenkov Chair of Neurology
2 Akkuratova street, St. Petersburg, 197341
41 Kirochnaya street, St. Petersburg, 191015
V. E. Druzhinina
Russian Federation
Valeriya E. Druzhinina – Student, Faculty of Medicine
41 Kirochnaya street, St. Petersburg, 191015
K. I. Sebelev
Russian Federation
Konstantin I. Sebelev – Dr. of Sci. (Med.), Full Professor, Head at the Department of Radiation Diagnostics No. 4, Leading Researcher at the Institute of Pathomorphology of the Nervous System
2 Akkuratova street, St. Petersburg, 197341
P. V. Lavrovsky
Russian Federation
Pavel V. Lavrovsky – Neurosurgeon of the Highest Qualification Category of the Neurosurgical Department
2 Akkuratova street, St. Petersburg, 197341
A. Yu. Ulitin
Russian Federation
Alexey Yu. Ulitin – Dr. of Sci. (Med.), Full Professor, Chief of Chair of Neurosurgery, Institute of Medical Education; Professor at the Polenov Chair of Neurosurgery
2 Akkuratova street, St. Petersburg, 197341
41 Kirochnaya street, St. Petersburg, 191015
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Review
For citations:
Vasilenko A.V., Druzhinina V.E., Sebelev K.I., Lavrovsky P.V., Ulitin A.Yu. Occipital-lobe epilepsy associated with intraparenchymal schwannoma in the occipital lobe: a modern perspective on the problem. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2024;16(2):138-149. (In Russ.) https://doi.org/10.56618/2071-2693_2024_16_2_138. EDN: KHHQWN