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Cerebral small vessel disease: illustration of a differential diagnosis on the example of a clinical case

Abstract

Cerebral disease of small vessels — a term referring to various pathological conditions and mechanisms that lead to damage to small vessels of white and gray matter of the brain, being an important cause of acute cerebrovascular accident, the development of cognitive impairment and complications of antithrombotic therapy. The article is devoted to the analysis of the differential diagnosis of cerebral amyloid angiopathy with other variants of cerebral disease of small vessels by the example of a clinical case. Is represented actual information on individual nosologies, Are described neuroimaging markers of cerebral amyloid angiopathy. Are examined the clinical manifestations of diseases, including cognitive impairment. Is highlighted the problem of making a diagnosis in this patient.

About the Authors

M. L. Pospelova
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



M. S. Krupenina
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



T. M. Alekseeva
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



D. M. Fedorov
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



T. А. Pavlova
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



N. E. Ivanova
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



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Review

For citations:


Pospelova M.L., Krupenina M.S., Alekseeva T.M., Fedorov D.M., Pavlova T.А., Ivanova N.E. Cerebral small vessel disease: illustration of a differential diagnosis on the example of a clinical case. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2020;12(3):67-73. (In Russ.)

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ISSN 2071-2693 (Print)