Прогноз исходов хирургического лечения фармакорезистентных форм эпилепсии (обзор литературы)

Хирургическое лечение широко используется в качестве эффективного метода лечения пациентов с фармакорезистентной эпилепсией. В многочисленных исследованиях сообщается об отсутствии приступов у 53– 84 % пациентов после переднемедиальной резекции височной доли. Риск серьезных хирургических осложнений с годами снизился и опустился ниже 1 % после резекции височной доли. Некоторые недавние серии исследований ставят под сомнение классическое представление о том, МР-негативная эпилепсия ассоциируется с неблагоприятным исходом хирургического лечения, что важно, учитывая большую долю пациентов с МР-негативной эпилепсией, которые рассматриваются для хирургического лечения. В обзоре рассмотрены результаты хирургического лечения фармакорезистентной эпилепсии, выявлены предикторы благоприятного и неблагоприятного исхода хирургического лечения, неврологические и когнитивные последствия, а также показатель качества жизни.

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