Diagnosis of a brain tumor in the practice of a neurologist and neurosurgeon: case report
Abstract
Gangliogliomas are mixed tumors of the central nervous system, consisting of well-differentiated neuronalglial elements of low malignancy (WHO Grade I). This category of tumors is characterized by slow growth, low morbidity and mortality. Gangliogliomas are found, as a rule, in children and young people; the most frequent localization is the temporal lobe, followed by the frontal, parietal and occipital lobes in frequency of occurrence. These tumors often manifest as epileptic seizures and account for approximately 40% of all epileptogenic tumors. It is known that timely surgical treatment in the volume of complete resection of ganglioglioma contributes to better control of seizures and improved longterm treatment results. As a result, the problem of early diagnosis of gangliogliomas and screening of molecular targets for therapy is very urgent. Considering the urgency of the problem, epidemiology and certain difficulties of primary clinical diagnosis, we present a description of a clinical case of an elderly patient with ganglioglioma.
About the Authors
M. L. PospelovaRussian Federation
St. Petersburg
I. K. Ternovykh
Russian Federation
St. Petersburg
V. A. Rudneva
Russian Federation
St. Petersburg
T. M. Alekseeva
Russian Federation
St. Petersburg
V. E. Olyushin
Russian Federation
St. Petersburg
A. Yu. Efimtsev
Russian Federation
St. Petersburg
K. K. Kukanov
Russian Federation
St. PetersburgSt. Petersburg
A. S. Lepekhina
Russian Federation
St. Petersburg
N. E. Ivanova
Russian Federation
St. Petersburg
A. Yu. Ulitin
Russian Federation
St. Petersburg
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Review
For citations:
Pospelova M.L., Ternovykh I.K., Rudneva V.A., Alekseeva T.M., Olyushin V.E., Efimtsev A.Yu., Kukanov K.K., Lepekhina A.S., Ivanova N.E., Ulitin A.Yu. Diagnosis of a brain tumor in the practice of a neurologist and neurosurgeon: case report. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2020;12(3):74-78. (In Russ.)