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Russian Neurosurgical Journal named after Professor A. L. Polenov

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Diagnosis of a brain tumor in the practice of a neurologist and neurosurgeon: case report

Abstract

Gangliogliomas are mixed tumors of the central nervous system, consisting of well-differentiated neuronalglial elements of low malignancy (WHO Grade I). This category of tumors is characterized by slow growth, low morbidity and mortality. Gangliogliomas are found, as a rule, in children and young people; the most frequent localization is the temporal lobe, followed by the frontal, parietal and occipital lobes in frequency of occurrence. These tumors often manifest as epileptic seizures and account for approximately 40% of all epileptogenic tumors. It is known that timely surgical treatment in the volume of complete resection of ganglioglioma contributes to better control of seizures and improved longterm treatment results. As a result, the problem of early diagnosis of gangliogliomas and screening of molecular targets for therapy is very urgent. Considering the urgency of the problem, epidemiology and certain difficulties of primary clinical diagnosis, we present a description of a clinical case of an elderly patient with ganglioglioma.

About the Authors

M. L. Pospelova
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



I. K. Ternovykh
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



V. A. Rudneva
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



T. M. Alekseeva
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



V. E. Olyushin
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



A. Yu. Efimtsev
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



K. K. Kukanov
Almazov National Medical Research Centre
Russian Federation

St. PetersburgSt. Petersburg



A. S. Lepekhina
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



N. E. Ivanova
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



A. Yu. Ulitin
Almazov National Medical Research Centre
Russian Federation

St. Petersburg



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Review

For citations:


Pospelova M.L., Ternovykh I.K., Rudneva V.A., Alekseeva T.M., Olyushin V.E., Efimtsev A.Yu., Kukanov K.K., Lepekhina A.S., Ivanova N.E., Ulitin A.Yu. Diagnosis of a brain tumor in the practice of a neurologist and neurosurgeon: case report. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2020;12(3):74-78. (In Russ.)

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ISSN 2071-2693 (Print)