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Late relapses of epileptic seizures after surgical treatment of epilepsy: a clinical case

https://doi.org/10.56618/2071-2693-2025-17-1-78

EDN: VZIIIY

Abstract

INTRODUCTION. Surgical treatment of drug-resistant epilepsy does not always allow to completely get rid of epileptic seizures. Relapses of seizures can occur both early and late after surgery.

AIM. To analyze a clinical case of late relapse of epileptic seizures after surgical treatment of drug-resistant epilepsy.

MATERIALS AND METHODS. The results of surgical treatment of a patient with drug-resistant epilepsy, with the development of relapse of epileptic seizures after 2 years and the decision to repeat surgical treatment, thanks to which it was possible to achieve remission of epileptic seizures, were analyzed.

RESULTS. The recurrence of seizures may be caused by incomplete removal of the epileptogenic focus or postoperative changes. In any case, a patient with persistent epileptic seizures is shown a preoperative examination and a decision on the need for reoperation.

CONCLUSION. Surgical treatment of drug-resistant epilepsy is the most effective method for achieving freedom from seizures or significantly reducing their frequency in the long term. Control over seizures in the postoperative period is usually ensured by taking antiepileptic drugs. The question of antiepileptic drugs withdrawal is still open. A personalized approach is used in each specific case.

About the Authors

V. D. Poleshchuk
Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation

Violetta D. Poleshchuk – Member of the SSS at the Department of Medical Genetics and Clinical Neurophysiology

1 Partizana Zheleznyak street, Krasnoyarsk, 660022  



I. G. Areshkina
Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation

Irina G. Areshkina – Assistant at the Department of Medical Genetics and Clinical Neurophysiology of the Institute of Postgraduate Education 

1 Partizana Zheleznyak street, Krasnoyarsk, 660022 



N. P. Utyashev
Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation

Nikita P. Utyashev – Applicant at the Department of Medical Genetics and Clinical Neurophysiology of the Institute of Postgraduate Education 

1 Partizana Zheleznyak street, Krasnoyarsk, 660022 



D. V. Dmitrenko
Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation

Diana V. Dmitrenko – Dr. of Sci. (Med.), Full Professor, Head at the Department of Medical Genetics and Clinical Neurophysiology of the Institute of Postgraduate Education, Head at the Neurological Center for Epileptology and Neurogenetics at the University Clinic 

1 Partizana Zheleznyak street, Krasnoyarsk, 660022 



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For citations:


Poleshchuk V.D., Areshkina I.G., Utyashev N.P., Dmitrenko D.V. Late relapses of epileptic seizures after surgical treatment of epilepsy: a clinical case. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2025;17(1):78-85. (In Russ.) https://doi.org/10.56618/2071-2693-2025-17-1-78. EDN: VZIIIY

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