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Hypersomnolence in patients in the acute period of ischemic stroke and its impact on the development of fatigue and anxiety-depressive disorders

https://doi.org/10.56618/2071-2693_2024_16_1_84

EDN: CDREJQ

Abstract

INTRODUCTION. Hypersomnolence spectrum disorders in patients in the acute period of ischemic stroke are one of the least studied topics. At the same time, of particular interest is the search for a possible relationship between fatigue and sleep and wakefulness disorders with anxiety and depression spectrum disorders.

AIM. To assess the dependence of hypersomnolence, fatigue, emotional and affective disorders on the volume, localization of the lesion and subtype of ischemic stroke.

MATERIALS AND METHODS. The study included 44 patients. During the examination, the subtype, pool and volume of the stroke focus were recorded. Fatigue, drowsiness, anxiety, and depression were assessed using the FIS, FSS, HADS, BDI-II, ESS, KSS scales, and filling out a sleep diary. Statistical data processing was performed using the StatPlus Mac (USA), Statistica 10.0 (USA) software package. The level of significance in testing statistical hypotheses was assumed to be p<0.05.

RESULTS. Data were obtained that hypersomnolence was characteristic of patients with an unspecified subtype of IS and right-sided localization of the lesion, regardless of the volume of the lesion. In patients with an unspecified subtype of IS and right-sided localization of stroke, the severity of anxiety and depression was less than in groups with other subtypes and lesions of the left hemisphere. In patients with hypersomnolence, the severity of anxiety and depression was significantly lower. Fatigue was not found to be associated with stroke subtype, lesion size and location, or with the presence or absence of IDS.

CONCLUSION. The established relationship between hypersomnolence and the stroke subtype, the affected hemisphere, and the severity of anxiety and depressive disorders can serve as a guideline for assessing and predicting stroke outcomes and developing an individual patient treatment strategy.

About the Authors

I. K. Ternovykh
V. A. Almazov National Medical Research Center
Russian Federation

Ternovykh Ivan Konstantinovich,

2, Akkuratova str., St. Petersburg, 197341. 



M. P. Topuzova
V. A. Almazov National Medical Research Center
Russian Federation

Topuzova Mariya Petrovna,

2, Akkuratova str., St. Petersburg, 197341. 



T. A. Shustova
V. A. Almazov National Medical Research Center
Russian Federation

Shustova Tat’yana Alekseevna,

2, Akkuratova str., St. Petersburg, 197341. 



A. F. Tsvetkova
V. A. Almazov National Medical Research Center
Russian Federation

Tsvetkova Alyona Fedorovna,

2, Akkuratova str., St. Petersburg, 197341. 



A. A. Khodot
V. A. Almazov National Medical Research Center
Russian Federation

Khodot Anna Aleksandrovna,

2, Akkuratova str., St. Petersburg, 197341. 



G. V. Belyakov
V. A. Almazov National Medical Research Center
Russian Federation

Belyakov Grigoriy Viktorovich,

2, Akkuratova str., St. Petersburg, 197341. 



T. M. Alekseeva
V. A. Almazov National Medical Research Center
Russian Federation

Alekseeva Tat’yana Mihayilovna,

2, Akkuratova str., St. Petersburg, 197341. 



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Review

For citations:


Ternovykh I.K., Topuzova M.P., Shustova T.A., Tsvetkova A.F., Khodot A.A., Belyakov G.V., Alekseeva T.M. Hypersomnolence in patients in the acute period of ischemic stroke and its impact on the development of fatigue and anxiety-depressive disorders. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2024;16(1):84-97. (In Russ.) https://doi.org/10.56618/2071-2693_2024_16_1_84. EDN: CDREJQ

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