Variants of cystic transformation of epiphisis: norm or pathology?
https://doi.org/10.56618/20712693_2022_14_3_115
Abstract
Increasing interest to a role of epiphysis (pineal gland) is explained both by its participation in regulation of human biorhythms, which is connected with production of melatonin, a hormone being one of factors of biorhythms regulation, and by close neuroendocrine mediation with hormonal and neurotransmitter activity of the brain.
With the advent of MRI, pineal cysts, the genesis of which is still largely unclear, as well as approaches to the frequency of examination, prognosis, etc., began to attract attention. This work considers aspects of the structure of the epiphysis and the involvement of the melatonin it produces in the pathogenesis of psychiatric disorders.
The study included 149 healthy volunteers aged 18 to 70 years divided into two groups: without morphological changes of the epiphysis according to MRI and with different types of cystic transformation. The results of the Spielberg questionnaire (personality anxiety) and the Stroop test (interference coefficient) revealed a correlation in patients with different types of cystic transformation, which reflects the presence of increased personality anxiety in patients with different variants of cystic transformation of the epiphysis compared to the group of persons without morphological changes.
Supporting agencies: The study was performed without external funding.
About the Authors
A. V. Shilova
V. M. Bekhterev National Medical Research Center of psychiatry and neurology
Russian Federation
Russian Federation
Shilova Anastasia Vitalievna
3 Bekhterev str., St. Petersburg, 192019
N. I. Ananyeva
V. M. Bekhterev National Medical Research Center of psychiatry and neurology
Russian Federation
Russian Federation
Ananieva Natalia Isaevna
3 Bekhterev str., St. Petersburg, 192019
L. N. Lukina
V. M. Bekhterev National Medical Research Center of psychiatry and neurology
Russian Federation
Russian Federation
Lukina Larisa Viktorovna
3 Bekhterev str., St. Petersburg, 192019
N. Yu. Safonova
V. M. Bekhterev National Medical Research Center of psychiatry and neurology
Russian Federation
Russian Federation
Safonova Natalia Yurevna
3 Bekhterev str., St. Petersburg, 192019
References
1. Anan’eva N.I., Lukina L. V., Andreev E. V., Tikhonov P. M. Gender features of normal age-related aging of the central nervous system. Database registration certificate 2021621983 dated 09/17/2021.
2. Ananyeva NI, Lukina LV, Andreev EV, Salomatina TA, Safonova NY, Parfyonova AV, Grebenshchikova RV. Gender differences in the volume of brain structures in the aspect of physiological aging. AdvGerontol. 2021;34(3):352–359. (In Russ.). PMID: 34409813
3. Le Bihan D. Apparent diffusion coefficient and beyond: what diffusion MR imaging can tell us about tissue structure. Radiology. 2013 Aug;268(2):318–22. doi: 10.1148/radiol.13130420
4. El Damaty A, Fleck S, Matthes M, Baldauf J, Schroeder HWS. Pineal Cyst without Hydrocephalus: Clinical Presentation and Postoperative Clinical Course AfterInfratentorialSupracerebell ar Resection. World Neurosurg. 2019 Sep; 129: e530-e537. doi: 10.1016/j.wneu.2019.05.200
5. Gaikova O. N., Anan’eva N.I., Zabrodskaya Yu. M. Morphological manifestations of general pathological processes in the nervous system. St. Petersburg, 2015. 158s. (In Russ.)]
6. Eide PK, Pripp AH, Ringstad GA. Magnetic resonance imaging biomarkers indicate a central venous hypertension syndrome in patients with symptomatic pineal cysts. J Neurol Sci. 2016 Apr 15;363:207–16. doi: 10.1016/j.jns.2016.02.038
7. Milton CK, Pelargos PE, Dunn IF. Headache outcomes after surgery for pineal cyst without hydrocephalus: A systematic review. SurgNeurolInt. 2020 Nov 11;11:384. doi: 10.25259/SNI_541_2020
8. Sirin S. et al. MRI-based assessment of the pineal gland in a large population of children aged 0–5 years and comparison with pineoblastoma: part II, the cystic gland //Neuroradiology.— 2016. — Т. 58.— № . 7. — С. 713–721.
9. D. Le Bihan, Apparent diffusion coefficient and beyond: what diffusion MR imaging can tell us about tissue structure, Radiology 268 (2013) 318 322.
Review
For citations:
Shilova A.V., Ananyeva N.I., Lukina L.N., Safonova N.Yu. Variants of cystic transformation of epiphisis: norm or pathology? Russian Neurosurgical Journal named after Professor A. L. Polenov. 2022;14(3):115-119. (In Russ.) https://doi.org/10.56618/20712693_2022_14_3_115
Views:
362
Email this article 