Two-component model of neurovegetative and metabolic stabilization in patients with complicated course of coronavirus infection Covid -19
Abstract
The problems associated with the treatment of severe forms of new coronavirus infection (NCI) encourage doctors and scientists to search for and use new drug regimens. SARS-CoV-2 causes a pronounced inflammatory, metabolic response of the body, endothelial damage, and the development of severe hypoxia. The central nervous system participates in the regulation of the inflammatory response of the body to a pathological agent, the implementation of the processes of sanogenesis. Creating conditions for the implementation of genetically embedded protective mechanisms is one of the main therapeutic tasks. Pharmacological protection of cells is more effective in conditions of stable functional state — neurovegetative stability. Optimal cytoprotective drugs in the conditions of «metabolic chaos» created by the NCI are drugs containing natural energy substrates. One of these drugs is Cytoflavin.ThE
AIM OF THE WORK is to provide a theoretical justification and practical confirmation of the feasibility of using a two-component model of neurovegetative and metabolic stabilization in patients with NCI.
METHODS : high doses of Cytoflavin, 50 ml per day, were administered to patients with severe NCI against the background of neurovegetative stabilization.
CONCLUSION: the introduction of high doses of Cytoflavin against the background of the created vegetative stability makes it possible to create an optimal level of metabolic protection of cells.
About the Authors
A. N. Kondratiev
“Polenov research Institute of Neurosurgery — branch of Almazov National medical research Centre”
Russian Federation
Russian Federation
Saint Petersburg
L. M. Tsentsiper
“Polenov research Institute of Neurosurgery — branch of Almazov National medical research Centre”
Russian Federation
Russian Federation
Saint Petersburg
V. V. Afanasiev
NW State medical university named after Ilia.I. Mechnikov
Russian Federation
Russian Federation
Saint Petersburg
Yu. S. Aleksandrovich
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Saint Petersburg
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Review
For citations:
Kondratiev A.N., Tsentsiper L.M., Afanasiev V.V., Aleksandrovich Yu.S. Two-component model of neurovegetative and metabolic stabilization in patients with complicated course of coronavirus infection Covid -19. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2022;14(1-2):59-66. (In Russ.)
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