Surgical treatment of neuronal-glial tumors in adults: current state of the problem and literature review
Abstract
RELEVANCE. Mixed neuronal-glial tumors (NGTs) are rare tumors of the central nervous system that consist of both neuronal and glial components. The surgical treatment of NGTs is primarily focused on the epileptic nature of the disease. In routine oncological operations, the degree of tumor resection is determined by minimizing the likelihood of recurrence. The optimal tactics of surgical treatment should take into account not only the epileptogenic nature of the disease, but also the oncological aspect — the likelihood of recurrence and malignant transformation. Nevertheless, at present, the question of the tactics of surgical treatment of NGTs is still open, the basic principles of choosing one or another method of surgical treatment have not been fully formulated. Over the past decade, isolated studies have been published in the literature devoted to a systematic review of the surgical treatment of the brain NGTs. most of these works are devoted to the treatment of such tumors mainly in children. There are no publications in the Russian literature devoted to the surgical treatment of NGTs in adults. This prompted us to write this literature review.
CONCLUSION. despite the lack of a clear surgical strategy, the first stages of consensus have emerged that defines a differentiated approach to the surgical treatment of cerebral NGTs.
About the Authors
B. S. Dombaanai
Burdenko National Medical research Center of neurosurgery
Russian Federation
Russian Federation
Moscow
D. I. Pitskhelauri
Burdenko National Medical research Center of neurosurgery
Russian Federation
Russian Federation
Moscow
L. V. Shishkina
Burdenko National Medical research Center of neurosurgery
Russian Federation
Russian Federation
Moscow
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Dombaanai B.S., Pitskhelauri D.I., Shishkina L.V. Surgical treatment of neuronal-glial tumors in adults: current state of the problem and literature review. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2022;14(1-2):148-153. (In Russ.)
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