Sporadic malignant melanotic nerve sheath tumor: rare clinical case
D. A. Murzaeva,
N. A. Mashkina,
E. N. Samoilova,
A. A. Prishchepov,
A. V. Simonov,
Y. M. Zabrodskaya https://doi.org/10.56618/2071-2693_2023_15_3_71
Abstract
ABSTRACT. Malignant melanotic nerve sheath tumor is rare disease which is characterized by aggressive clinical course. In classification of tumors CNS WHO 2021 has been changed its position from benign to malignant nerve tumors, however, there are not guidelines for treatment such patients.
CASE REPORT. We present a rare case of MM NST in a 36-year-old woman with a paravertebral tumor of Th4-Th6 vertebrae, without metastases, mitosis, necrosis, invasive growth, with low proliferative activity, also presence of capsule, cystic component, growth from nerve — these features help distinguish from melanoma.
CONCLUSION. The clinical case of a rare nerve tumor underscores the key importance of morphological research in determining the degree of anaplasia of nerve tumors.
About the Authors
D. A. Murzaeva
Polenov Russian Scientific Research Institute of Neurosurgery — branch of Almazov National Medical Research Centre;
Federal State Budgetary Educational Institution of Higher Education “Tyumen State Medical University”;
State autonomous health care institution Multidisciplinary Clinical Medical Center “Medical City”
Russian Federation
Russian Federation
Dzhamilia A. Murzaeva
Saint Petersburg, 191014, Russia
Tyumen, 625023, Russia
625041, Tyumen, Russia
N. A. Mashkina
GBUZ TO «Regional Clinical Hospital № 1»
Russian Federation
Russian Federation
Mashkina Natalia Anatolyevna
Tyumen, 625062, Russia
E. N. Samoilova
Federal State Budgetary Educational Institution of Higher Education “Tyumen State Medical University”
Russian Federation
Russian Federation
Samoilova Elizaveta Nikolayevna
Tyumen, 625023, Russia
A. A. Prishchepov
Federal State Budgetary Educational Institution of Higher Education “Tyumen State Medical University”;
State autonomous health care institution Multidisciplinary Clinical Medical Center “Medical City”
Russian Federation
Russian Federation
Prishchepov Aleksandr Anatolievich
Tyumen, 625023, Russia
625041, Tyumen, Russia
A. V. Simonov
State autonomous health care institution Multidisciplinary Clinical Medical Center “Medical City”
Russian Federation
Russian Federation
Alexey V. Simonov
625041, Tyumen, Russia
Y. M. Zabrodskaya
Polenov Russian Scientific Research Institute of Neurosurgery — branch of Almazov National Medical Research Centre
Russian Federation
Russian Federation
Yulya M. Zabrodskaya
Saint Petersburg, 191014, Russia
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Review
For citations:
Murzaeva D.A., Mashkina N.A., Samoilova E.N., Prishchepov A.A., Simonov A.V., Zabrodskaya Y.M. Sporadic malignant melanotic nerve sheath tumor: rare clinical case. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2023;15(3):71-76. (In Russ.) https://doi.org/10.56618/2071-2693_2023_15_3_71
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