Предоперационная эмболизация в хирургическом лечении метастатической болезни позвоночника: современное состояние проблемы. Обзор литературы
Аннотация
Резюме: предоперационная эмболизация сосудистой сети опухоли является широко распространенным методом уменьшения интраоперационной кровопотери в хирургическом лечении метастазов в позвоночник, однако, до настоящего момента остаются дискутабельными многие аспекты практического применения данного метода. В статье приведен обзор доступной литературы в библиографических базах данных. Исследование проведено по следующим критериям включения: трансартериальная эмболизация, прямая эмболизация, интраоперационная кровопотеря, сроки хирургического лечения, эмолизирующий материал, гиперваскулярные метастазы, гиповаскулярные метастазы, осложнения. Дополнительное изучение проблемы проведено по спискам литературы найденных статей.
Об авторах
А. С. Назаров
РНХИ им. проф. А. Л. Поленова — филиал ФГБУ «НМИЦ им. В. А. Алмазова»
Россия
Россия
Назаров Александр Сергеевич
Санкт-Петербург
А. Ю. Орлов
РНХИ им. проф. А. Л. Поленова — филиал ФГБУ «НМИЦ им. В. А. Алмазова»
Россия
Россия
Орлов Андрей Юрьевич
Санкт-Петербург
А. Ю. Улитин
РНХИ им. проф. А. Л. Поленова — филиал ФГБУ «НМИЦ им. В. А. Алмазова»
Россия
Россия
Улитин Алексей Юрьевич
Санкт-Петербург
А. В. Кудзиев
РНХИ им. проф. А. Л. Поленова — филиал ФГБУ «НМИЦ им. В. А. Алмазова»
Россия
Россия
Кудзиев Андрей Валерьевич
Санкт-Петербург
Ю. В. Беляков
РНХИ им. проф. А. Л. Поленова — филиал ФГБУ «НМИЦ им. В. А. Алмазова»
Россия
Россия
Беляков Юрий Владимирович
Санкт-Петербург
Список литературы
1. W orld Health Organization. 2018 Sep 12. Cancer 2018 URL : https:// www.who.int/news-room/fact-sheets/detail/cancer [accessed 2019–11–06].
2. Каприн А. Д. Злокачественные новообразования в России в 2018 году (заболеваемость и смертность). — А. Д. Каприн, В. В. Старинский, Г. В. Петрова. — М.: МНИОИ им. П. А. Герцена — филиал ФГБУ «НМИЦ радиологии» Минздрава России, 2019. — илл. — 250 с.
3. National Collaborating Centre for Cancer (UK): National Institute for Health and Clinical Excellence: Guidance. In metastatic spinal cord compression: diagnosis and management of patients at risk of or with metastatic spinal cord compression. Cardiff (UK): National Collaborating Centre for Cancer (UK), 2008.
4. Barzilai, O. Integrating evidence-based medicine for treatment of spinal metastases into a decision framework: neurologic, oncologic, mechanicals stability, and systemic disease / O. Barzilai, I. L aufer, Y. Y amada, et al. // J Clin Oncol. — 2017. — Vol. 35. — P. 2419–2427.
5. Barzilai, O. P redictors of quality of life improvement after surgery for metastatic tumors of the spine: prospective cohort study / O. Barzilai, L. M cLaughlin, M. K. A mato, et al. // Spine J. — 2018. — Vol. 18. — P. 1109–1115.
6. Y oshihara, H. Trends in the surgical treatment for spinal metastasis and the in-hospital patient outcomes in the United States from 2000 to 2009 / H. Y oshihara, D. Y oneoka // Spine J. — 2014. — Vol. 14. — P. 1844–1849.
7. Sohn, S. A nationwide epidemiological study of newly diagnosed spine metastasis in the adult Korean population / S. Sohn, J. Kim, C. K. C hung, et al. // Spine J. — 2016. — Vol. 16. — P. 937–945.
8. P ennington, Z. M inimally invasive versus conventional spine surgery for vertebral metastases: a systematic review of the evidence / Z. P ennington, A. K. A hmed, C. A . M olina, J. E hresman, I. L aufer, D. M . Sciubba // Ann Transl Med. — 2018. — Vol. 6. — P. 103.
9. Guzik, G. O utcomes of Corpectomy in Patients with Metastatic Cancer / G. Guzik // Ortop Traumatol Rehabil. — 2017. — Vol. 19(1). — P. 23–32.
10. M urakami, H. Total en bloc spondylectomy for lung cancer metastasis to the spine / H. M urakami, N. Kawahara, S. D emura, S. Kato, K. Y oshioka, K. Tomita // J Neurosurg Spine. — 2010. — Vol. 13. — P. 414–417.
11. O ka, S. Total or partial vertebrectomy for lung cancer invading the spine / S. O ka, H. M atsumiya, S. Shinohara, et al. // Ann Med Surg (Lond). — 2016. — Vol. 12. — P. 1–4.
12. Kaloostian, P. E . C urrent paradigms for metastatic spinal disease: an evidence-based review / P. E . Kaloostian, A. Y urter, P. L . Zadnik, D. M . Sciubba, Z. L . Gokaslan //Ann Surg Oncol. — 2014. — Vol. 21. — P. 248–262.
13. Zadnik, P. L . P rolonged survival following aggressive treatment for metastatic breast cancer in the spine / P. L . Zadnik, L. Hwang, D. G. J u, et al. // Clin Exp Metastasis. — 2014. — Vol. 31. — P. 47–55.
14. Goodwin, C.R. A systematic review of clinical outcomes for patients diagnosed with skin cancer spinal metastases / C. R . Goodwin, E. W . Sankey, A. L iu, et al.// J Neurosurg Spine. — 2015. — Vol. 24. — P. 837–849.
15. Y ang, L. P atient Characteristics Following Surgery for Spinal Metastases: A Multicenter Retrospective Study / L. Y ang, F. W ang, H. Zhang, et al.// Orthop Surg. — 2019. — Vol. 11(6). P. 1039–1047.
16. Tang, B. R isk factors for major complications in surgery for hypervascular spinal tumors: an analysis of 120 cases with adjuvant preoperative embolization / B. Tang, T. J i, X. Tang, L. J in, S. D ong, W. Guo // Eur Spine J. — 2015. — Vol. 24. — P. 2201–2208.
17. Kato, S. P reoperative embolization significantly decreases intraoperative blood loss during palliative surgery for spinal metastasis / S. Kato, H. M urakami, T. M inami, et al. // Orthopedics. — 2012. — Vol. 35. — P. e1389–95.
18. Nair, S. P reoperative embolization of hypervascular thoracic, lumbar, and sacral spinal column tumors: technique and outcomes from a single center / S. Nair, Y. P . Gobin, L. Z. L eng, et al.// Interv Neuroradiol. — 2013. — Vol. — 19. — P. 377–385.
19. M avrogenis, A. F. P alliative embolization for osteosarcoma / A. F. M avrogenis, G. R ossi, E. R imondi, et al.// Eur J Orthop Surg Traumatol. — 2014. — Vol. 8. — P. 1351–1356.
20. C lausen, C. P reoperative embolization in surgical treatment of spinal metastases: single-blind, randomized controlled clinical trial of efficacy in decreasing intraoperative blood loss / C. C lausen, B. D ahl, S. C . Frevert, et al. // J Vasc Interv Radiol. — 2015. — Vol. 26. — P. 402–412.
21. R obial, N. Is preoperative embolization a prerequisite for spinal metastases surgical management? / N. R obial, Y. P . C harles, I. Bogorin, et al. // Orthop Traumatol Surg Res. — 2012. — Vol. 98. — P. 536–542.
22. Kobayashi, K. P reoperative embolization of spinal tumors: variables affecting intraoperative blood loss after embolization / K. Kobayashi, E. O zkan, A. Tam, et al. // Acta Radiol. — 2012. — Vol. 53. — P. 935–942.
23. Kato, S. O ptimal schedule of preoperative embolization for spinal metastasis surgery / S. Kato, T. Hozumi, Y. Takaki, et al. // Spine (Phila Pa 1976). — 2013. — Vol. 38. — P. 1964–1969.
24. W ilson, M. A . R etrospective analysis of preoperative embolization of spinal tumors / M. A . W ilson, D. L . C ooke, B. Ghodke, et al.// AJ NR Am J Neuroradiol. — 2010. — Vol. 31. — P. 656–660.
25. Thiex, R. The role of preoperative transarterial embolization in spinal tumors. A large single-center experience / R. Thiex, M. B. Harris, C. Sides, C. M . Bono, K. U . Frerichs // Spine J. — 2013. — Vol. 13. — P. 141–149.
26. Zhang, J. P re-operative embolisation of spinal tumours: neither neglect the neighbour nor blindly follow the gold standard / J. Zhang, N. S. Kumar, B.W.L. Tan, L. Shen, G. A nil // Neurosurg Rev. — 2019. — Vol. 42(4). — P. 951–959.
27. P rabhu, V. C . R esults of preoperative embolization for metastatic spinal neoplasms / V. C . P rabhu, M. H. Bilsky, K. J ambhekar, et. al. // J Neurosurg. — 2003. — Vol. 98(2 Suppl). — P. 156–164.
28. Qiao, Z. D oes preoperative transarterial embolization decrease blood loss during spine tumor surgery? / Z. Qiao, N. J ia, Q. He // Interv Neuroradiol. — 2015. — Vol. 21. — P. 129–35.
29. P tashnikov, D. P reoperative embolization versus local hemostatic agents in surgery of hypervascular spinal tumors / D. P tashnikov, N. Zaborovskii, D. M ikhaylov, S. M asevnin // Int J Spine Surg. — 2014. — Vol. 8.
30. Hong, C. G. P reoperative embolization in patients with metastatic spinal cord compression: mandatory or optional? / C. G. Hong, J. H. C ho, D. C . Suh, et al. // World J Surg Oncol. — 2017. — Vol. 15. — P. 45.
31. Yoo, S. L . C linical significance of preoperative embolization for nonhypervascular metastatic spine tumors /S.L. Yoo, et al. // J Korean Neurosurg Soc. — 2019. — Vol. 62 (1). — P. 106–113.
32. O mid-Fard, N. The evolution of pre-operative spine tumour embolization / N. O mid-Fard, C. G. Fisher, M. K. Heran // Br J Radiol. — 2019. — Vol. 92(1100). — P. 20180899.
33. Vaidya, S. A n Overview of Embolic Agents / S. Vaidya, K. R . Tozer, J. C hen // Semin Intervent Radiol. — 2008. — Vol. 25(3). — P. 204–215.
34. Feldman, F. Selective intra-arterial embolization of bone tumors. A useful adjunct in the management of selected lesions / F. Feldman, W. J . C asarella, H. M . D ick, et al.// Am J Roentgenol Radium Ther Nucl Med. — 1975. — Vol. 123. — P. 130–139.
35. Hess, T. U se of preoperative vascular embolisation in spinal metastasis resection / T. Hess, B. Kramann, E. Schmidt, et al.// Arch Orthop Trauma Surg. — 1997. — Vol. 116. — P. 279–282.
36. Heran, M. K. P reoperative embolization of spinal metastatic disease: rationale and technical considerations / M. K. Heran // Semin Musculoskelet Radiol. — 2011. — Vol. 15(02). — P. 135–142.
37. Berkefeld, J. Hypervascular spinal tumors: influence of the embolization technique on perioperative hemorrhage / J. Berkefeld, D. Scale, J. Kirchner, T. Heinrich, J. Kollath // AJ NR Am J Neuroradiol. — 1999. — Vol. 20. — P. 757–763.
38. Smit, J. W . E mbolization of skeletal metastases in patients with differentiated thyroid carcinoma / J. W . Smit, T. P . L inks, G. M . Hew, et al.// Ned Tijdschr Geneeskd. — 2000. — Vol. 144. — P. 1406–1410.
39. Basile, A. Trisacryl gelatin microspheres versus polyvinyl alcohol particles in the preoperative embolization of bone neoplasms / A. Basile, T. R and, F. L omoschitz, et al.// Cardiovasc Intervent Radiol. — 2004. — Vol. 27. — P. 495–502.
40. Ghobrial, G. M . P reoperative spinal tumor embolization: An institutional experience with Onyx / G. M . Ghobrial, N. C halouhi, J. Harrop, et al. // Clin Neurol Neurosurg. — 2013. — Vol. 115. — P. 2457–2463.
41. C ernoch, P. P re-operative embolisation of spinal metastasis: technique, complication rate and outcome-clinical experience / P. C ernoch, L. Hechelhammer, A. von Hessling, et al. // Int Orthop. — 2015. — Vol. 39(7). — P. 1399–1404.
42. W irbel, R. J . P reoperative embolization in spinal and pelvic metastases / R. J . W irbel, R. R oth, M. Schulte, et al. // J Orthop Sci. — 2005. — Vol. 10. — P. 253–257.
43. R adeleff, B. Transarterial embolization of primary and secondary tumors of the skeletal system / B. R adeleff, M. E iers, R. L opez-Benitez, et al. // Eur J Radiol. — 2006. — Vol. 58. — P. 68–75.
44. Ozkan, E. E mbolization of spinal tumors: vascular anatomy, indications, and technique / E. O zkan, S. Gupta // Tech Vasc Interv Radiol. — 2011. — Vol. 14. — P. 129–140.
45. Quraishi, N. A . O utcome of embolised vascular metastatic renal cell tumours causing spinal cord compression / N. A . Quraishi, S. P urushothamdas, S. R . M anoharan, et al. // Eur spine J. — 2013. — Vol. 22. — P. 27–32.
46. Tang, B. W hich is the better timing between embolization and surgery for hypervascular spinal tumors, the same day or the next day? A retrospective comparative study / B. Tang, T. J i, W. Guo, et al. // Medicine (Baltimore). — 2018. — Vol. 97(23). — P. e10912.
47. Schmidt, R. Surgical therapy of vertebral metastases. Are there predictive parameters for intraoperative excessive blood loss despite preoperative embolization? / R. Schmidt, G. R upp-Heim, F. D ammann, C. U lrich, J. Nothwang // Tumori. — 2011. — Vol. 97. — P. 66–73.
48. P atsalides, А. P reoperative catheter spinal angiography and embolization of cervical spinal tumors: Outcomes from a single center / А. P atsalides, L. L eng, D. Kimball, et al. // Interv Neuroradiol. — 2016. — Vol. 22(4). — P. 457–465.
49. A lbuquerque, F. C . E ndovascular management of intracranial vertebral artery dissecting aneurysms / F. C . A lbuquerque, D. J . Fiorella, P. P . Han, et al. // Neurosurg Focus. — 2005. — Vol. 18. — P. E3.
50. Zoarski, G. H. Safety of unilateral endovascular occlusion of the cervical segment of the vertebral artery without antecedent balloon test occlusion / G. H. Zoarski, R. Seth // Am J Neuroradiol. — 2014. — Vol. 35. — P. 856–861.
51. O gungbemi, А. P ermanent endovascular balloon occlusion of the vertebral artery as an adjunct to the surgical resection of selected cervical spine tumors: A single center experience / A. O gungbemi, V. E lwell, D. C hoi, F. R obertson // Interv Neuroradiol. — 2015. — Vol. 21. — P. 532–537.
52. Finstein, J. L . P ostembolization paralysis in a man with thoracolumbar giant cell tumor / J. L . Finstein, K. R . C hin, F. A lvandi, et al. // Clin Orthop Relat Res. — 2006. — Vol. 453. — P. 335–340.
53. Fernandez-Torron, R. Brown-sequard syndrome after endovascular embolization of vertebral hemangioma / R. Fernandez-Torron, J. A . P alma, M. R iverol, et al.// Spinal Cord. — 2012. — Vol. 50. — P. 636–637.
54. U eda, Y. Influence on spinal cord blood flow and function by interruption of bilateral segmental arteries at up to three levels: experimental study in dogs / Y. U eda, N. Kawahara, K. Tomita, et al. // Spine. — 2005. — Vol. 30. — P. 2239–2243.
55. Kato, S. E ffects on spinal cord blood flow and neurologic function secondary to interruption of bilateral segmental arteries which supply the artery of Adamkiewicz: an experimental study using a dog model / S. Kato, N. Kawahara, K. Tomita, et al. // Spine. — 2008. — Vol. 33. — P. 1533–1541.
56. M urakami, H. D oes interruption of the artery of Adamkiewicz during total en bloc spondylectomy affect neurologic function? / H. M urakami, N. Kawahara, K. Tomita, S. D emura, S. Kato, K. Y oshioka // Spine. — 2010. — Vol. 35. — P. E1187-E1192.
57. Kieffer, E. Spinal cord arteriography: a safe adjunct beforedescending thoracic or thoracoabdominal aortic aneurysmectomy / E. Kieffer, S. Fukui, J. C hiras, et al. // J Vasc Surg. — 2002. — Vol. 35. — P. 262–268.
58. O rchowski, J. Neurological deficit from a purely vascular etiology after unilateral vessel ligation during anterior thoracolumbar fusion of the spine / J. O rchowski, K. H. Bridwell, L. G. L enke // Spine. — 2005. — Vol. 30. — P. 406–410.
59. Tsirikos, A. I. Segmental vessel ligation in patients undergoing surgery for anterior spinal deformity / A. I. Tsirikos, S. P . Howitt, M. J . M cMaster // J Bone Joint Surg Br. — 2008. — Vol. 90–B. — P. 474–479.
60. C harles, Y. P . R elevance of the anatomical location of the Adamkiewicz artery in spine surgery / Y. P . C harles, B. Barbe, J. P . Steib, et al. // Surg Radiol Anat. — 2011. — Vol. 33(1). — P. 3–9.
61. R am, S. Spinal cord infarction secondary to intervertebral foraminal disease / S. R am, A. O sman, V. N. C assar-Pullicino, et al. // Spinal Cord. — 2004. — Vol. 42. — P. 481–484.
62. R owland, J. W . C urrent status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon / J. W . R owland, G. W . Hawryluk, B. Kwon, et al. // Neurosurg Focus. — 2008. — Vol. 25(5). — P. E2.
63. M artirosyan, N. L . Blood supply and vascular reactivity of the spinal cord under normal and pathological conditions / N. L . M artirosyan, J. S. Feuerstein, N. Theodore, et al. // J Neurosurg Spine. — 2011. — Vol. 15. — P. 238–251.
64. Grelat, M. A im and indications of spinal angiography for spine and spinal cord surgery: Based on a retrospective series of 70 cases / M. Grelat, R. M adkouri, J. Tremlet, et al.// Neurochirurgie. — 2015. — Vol. 62. — P. 38–42.
65. M ariani, L. A rteriovenous shunt measurement during endovascular therapy for cerebrospinal lesions / L. M ariani, A. R . Haldemann, G. Schroth// AJ NR Am J Neuroradiol. — 1997. — Vol. 18. — P. 1679–1689.
66. Schirmer, C. M . P reoperative embolization of hypervascular spinal metastases using percutaneous direct injection with n-butyl cyanoacrylate: technical case report / C. M . Schirmer, A. M . M alek, E. S. Kwan, D. A . Hoit, S. J . W eller // Neurosurgery. — 2006. — Vol. 59(2). — P. E431–432.
67. L orincz, T. A lterations of microvascular density in bone metastases of adenocarcinomas / T. L orincz, J. Timar, M. Szendroi // Pathol Oncol Res. — 2004. — Vol. 10. — P. 149–153.
68. C hiras, J. P ercutaneous injection of an alcoholic embolizing emulsion as an alternative preoperative embolization for spine tumor / J. C hiras, C. C ognard, M. R ose, et al.// AJ NR Am J Neuroradiol. — 1993. — Vol. 14. — P. 1113–1117.
69. Trystram, D. P reoperative devascularization of a vertebral metastasis with a spinal artery at the same level / D. Trystram, A. A ymard, S. Godon Hardy, et al. // J Radiol. — 2000. — Vol. 81. — P. 250–253.
70. C asasco, A. D evascularization of craniofacial tumors by percutaneous tumor puncture / A. C asasco, D. Herbreteau, E. Houdart, et al. // AJ NR Am J Neuroradiol. — 1994. — Vol. 15. — P. 1233–1239.
71. C asasco, A. M ajor complications of percutaneous embolization of skull-base tumors / A. C asasco, E. Houdart, A. Biondi, et al. // AJ NR Am J Neuroradiol. — 1999. — Vol. 20. — P. 179–181.
72. E l Hindy, N. Spinal metastasis from malignant meningeal intracranial hemangiopericytoma: one-staged percutaneous Onyx™ embolization and resection — a technical innovation / N. E l Hindy, A. R ingelstein, M. Forsting, U. Sure, O. M ueller // World J Surg Oncol. — 2013. — Vol. 11. — P. 152.
73. C larençon, F. O nyx injection by direct puncture for the treatment of hypervascular spinal metastases close to the anterior spinal artery: initial experience / F. C larençon, F. D i Maria, E. C ormier, et al.// J Neurosurg Spine. — 2013. — Vol. 18(6). — P. 606–610.
74. Y ao, K. C . Transpedicular N-butyl cyanoacrylate-mediated percutaneous embolization of symptomatic vertebral hemangiomas / K. C . Y ao, A. M . M alek // J Neurosurg Spine. — 2013. — Vol. 18. — P. 450–455.
75. L im, K. Z. P re-operative embolization of hypervascular spinal metastasis using percutaneous direct intra-tumoural injection with Onyx under local anesthesia / K. Z. L im, T. Goldschlager, R. V. C handra // J Clin Neurosci. — 2017. — Vol. 44. — P. 306–309.
76. M ashaly, H. Intraoperative transpedicular Onyx injection to reduce vascularity of a thoracic hemangiopericytoma after unsuccessful preoperative endovascular embolization: a technical report / H. M ashaly, Z. Zhang, A. Shaw, P. Y oussef, E. M endel // Oper Neurosurg (Hagerstown). — 2018. — Vol. 14(2). — P. E17-E22.
Рецензия
Для цитирования:
Назаров А.С., Орлов А.Ю., Улитин А.Ю., Кудзиев А.В., Беляков Ю.В. Предоперационная эмболизация в хирургическом лечении метастатической болезни позвоночника: современное состояние проблемы. Обзор литературы. Российский нейрохирургический журнал имени профессора А. Л. Поленова. 2020;12(4):80-89.
For citation:
Nazarov A.S., Orlov A.Yu., Ulitin A.Yu., Kudziev A.V., Belyakov Yu.V. Preoperative emboliza tion in surgery of metastatic spinal disease : current state of the problem. A literature review. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2020;12(4):80-89. (In Russ.)
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