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linical and mri features of m alignant multiple sclerosis

Abstract

Object: to analyze the clinical and MRI characteristics of cin patients with malignant course to predict the development of the disease.
Methods: Two groups of patients with multiple sclerosis were formed: malignant and benign multiple sclerosis. All patients underwent an assessment of the anamnesis, the severity of neurological disorders, magnetic resonance imaging in the debut and during treatment of the disease.
Findings : The duration of the first remission was significantly shorter in patients in the first group. On the first MRI, significantly more T2 foci were observed in patients with malignant multiple sclerosis. Also, in the first group, spinal cord lesions were significantly more often diagnosed.
Conclusions : Thus, the most significant predictors of the malignant multiple sclerosis were motor disorders at onset, short first remission, more than 20 foci of demyelination on MRI at onset of the disease, the presence of focal lesions of the spinal cord substance.

About the Authors

E. V. Kiseleva
Yaroslavl State Medical University
Russian Federation


N. V. Spirin
Yaroslavl State Medical University
Russian Federation


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Kiseleva E.V., Spirin N.V. linical and mri features of m alignant multiple sclerosis. Russian Neurosurgical Journal named after Professor A. L. Polenov. 2021;13(2):39-42. (In Russ.)

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ISSN 2071-2693 (Print)